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iloperidone increases levels of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Iloperidone is often a time-dependent CYP3A inhibitor and may result in increased plasma levels of drugs predominantly eliminated by CYP3A4.Langtidsbruk Leger som forskriver modafinil for en lengre periode, skal jevnlig